Comparative Sequence Analysis   

Changes from version 2.0 to 3.0

• Digest output
  SMART now only produces a single diagram representing a 'best' interpretation of all the annotation that has been performed. A comprehensive summary of the results is also provided in table format.
• selective SMART
  Selective SMART allows to look for proteins with combinations of specific domains in different species or taxonomic ranges.
• alert SMART
  The SMART database gets updated about once a week. If you are interested in specific domains or combination of them in specific taxonomic ranges, you can use the SMART alerting service. This provides the identities of newly-deposited proteins that match your query.
• Domain queries
  You can ask for proteins having the same domain order / composition as your query protein.
• SMARTed Genomes
  You can get the result of SMARTing the genomes of Caenorhabditis elegans and Saccharomyces cerevisiae via the annotation pages.
• Faster PFAM searches
  The PFAM searches now runs on a PVM cluster.